Detalhe da pesquisa
1.
An antibiotic from an uncultured bacterium binds to an immutable target.
Cell
; 186(19): 4059-4073.e27, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37611581
2.
An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis.
PLoS Pathog
; 19(2): e1011047, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36730465
3.
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates.
Proc Natl Acad Sci U S A
; 118(47)2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785593
4.
Modular Synthesis of Halogenated Xanthones by a Divergent Coupling Strategy.
J Org Chem
; 87(14): 9375-9383, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35776916
5.
A new antibiotic kills pathogens without detectable resistance.
Nature
; 517(7535): 455-9, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25561178
6.
Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action.
Int J Mol Sci
; 22(20)2021 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681833
7.
Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin.
Angew Chem Int Ed Engl
; 60(24): 13579-13586, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33768646
8.
Modular Total Synthesis of Farnesyl Analogues of Cell Wall Precursors Lipid I and II Containing the Staphylococcus aureus Pentaglycine Bridge Modification.
J Org Chem
; 85(15): 10206-10215, 2020 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571025
9.
Cacaoidin, First Member of the New Lanthidin RiPP Family.
Angew Chem Int Ed Engl
; 59(31): 12654-12658, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407589
10.
Radiomics of Brain MRI: Utility in Prediction of Metastatic Tumor Type.
Radiology
; 290(2): 479-487, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30526358
11.
Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains.
Proc Natl Acad Sci U S A
; 113(45): E7077-E7086, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791134
12.
Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets.
PLoS Pathog
; 12(5): e1005585, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27144276
13.
Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.
Int J Med Microbiol
; 308(3): 335-348, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29429584
14.
Antimicrobial Dialkylresorcins from Marine-Derived Microorganisms: Insights into Their Mode of Action and Putative Ecological Relevance.
Planta Med
; 84(18): 1363-1371, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29991081
15.
Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway.
J Biol Chem
; 291(5): 2535-46, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26620564
16.
Targeting a cell wall biosynthesis hot spot.
Nat Prod Rep
; 34(7): 909-932, 2017 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28675405
17.
The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus.
Int J Med Microbiol
; 307(1): 1-10, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989665
18.
Biosynthetic Studies on Acetosellin and Structure Elucidation of a New Acetosellin Derivative.
Planta Med
; 83(12-13): 1044-1052, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28081580
19.
Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis.
Antimicrob Agents Chemother
; 60(11): 6510-6517, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27550357
20.
Erratum: A new antibiotic kills pathogens without detectable resistance.
Nature
; 520(7547): 388, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25731174